How to work with USB-Serial in OSx

WCH341 based hardware

Unfortunately, no tty device presented, only userspace hardware. You can download application from here

PL2303 based hardware

Firstly download a kext from link and put to the /System/Library/Extensions Then load kext and rebuild cache

cd /System/Library/Extensions
kextload ./osx-pl2303.kext
kextcache -system-cache

Then you can use your adapter from CLI

sudo cu -l /dev/tty.PL2303-000012FD